I've been running Audition flawlessly for quite some time. No issues to speak of.
I decided to create a keyboard shortcut today. Instant crash. 
I repeated the process several times with the same result. I restarted. I re-installed Audition. I updated to build 5.0.2. No change.
iMac 10.8.3, Adobe Audition CS6 build 5.0.2